UPSC Science and Technology

Strengthening CAR T-Cell Therapy

Researchers at the Indian Institute of Technology Bombay have developed a gentler method to recover lab-grown T-cells, a crucial step in CAR T-cell therapy. Using the mild enzyme Accutase instead of harsher alternatives helps improve cell survival and preserve immune function. The approach enhances the reliability and efficiency of immunotherapy production, supports cost reduction, and strengthens India’s efforts to make advanced cancer treatments more affordable and accessible.

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NATIONAL TECHNOLOGY READINESS ASSESSMENT FRAMEWORK (NTRAF)

The National Technology Readiness Assessment Framework, launched by the Principal Scientific Adviser, standardises innovation evaluation using a 9-level TRL scale. Developed with Confederation of Indian Industry, it bridges the lab-to-market gap, guides evidence-based funding, and supports Anusandhan National Research Foundation in strengthening India’s deeptech ecosystem and self-reliance.

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