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About Zika Virus:
Zika is a mosquito-borne virus identified in Uganda in 1947. The infection, often mild and self-limiting, poses significant risks to pregnant women and their fetuses, leading to microcephaly in newborns. It is also linked to Guillain-Barré syndrome, a rare nerve disorder causing muscle weakness and paralysis.
| 
 Virus  | 
 Zika virus (Flavivirus genus, Flaviviridae family)  | 
| 
 Transmission  | 
 Aedes species mosquito (Aedes aegypti and Aedes albopictus)  | 
| 
 Associated Diseases  | 
 Microcephaly in newborns, Guillain-Barré syndrome  | 
| 
 First Discovery  | 
 Zika Forest, Uganda, 1947  | 
| 
 First Human Case  | 
 1952  | 
| 
 Significant Epidemic  | 
 Brazil, 2015  | 
| 
 WHO Declaration  | 
 Public Health Emergency of International Concern (PHEIC), 2016  | 
| 
 Spread in India (2018)  | 
 Gujarat, Madhya Pradesh, Rajasthan  | 
| 
 Spread in India (2021)  | 
 Kerala, Maharashtra  | 
| 
 Microcephaly in India  | 
 Not recorded  | 
Microdetails about the Zika Virus:
| 
 Virus Structure  | 
 Single-stranded RNA virus, Flaviviridae family  | 
| 
 Lineages  | 
 Asian and African lineages  | 
| 
 Hosts  | 
 African lineage: Monkeys and apes (primary), humans (secondary) Asian lineage: Humans (primary)  | 
| 
 Structural Proteins  | 
 Capsid (C), membrane (M), envelope (E)  | 
| 
 Nonstructural Proteins  | 
 Seven proteins aiding in genome replication, packaging, and host manipulation  | 
| 
 Discovery Technique  | 
 Cryo-electron microscopy revealed near-atomic structure for the first time  | 
| 
 Transmission Modes  | 
 Infected Aedes aegypti mosquito bite, sexual contact, blood transfusion, organ transplantation, congenital infection  | 
| 
 Testing  | 
 Detection of viral RNA in blood, saliva, urine, cerebrospinal fluid, amniotic fluid, semen, and breast milk  | 
| 
 Symptoms  | 
 Incubation: 3-12 days post-bite Common: Maculopapular rash, arthralgia, fatigue, conjunctivitis, myalgia, headache  | 
| 
 Less Common Symptoms  | 
 Retro-orbital pain, gastrointestinal symptoms  | 
| 
 Treatment  | 
 No vaccine/preventative treatment Symptomatic: Hydration, pain relief, antihistamines  | 
| 
 Control Measures  | 
 Regular vector surveillance, integrated vector management  | 
| 
 Integrated Vector Management  | 
 Environmental modification, protective clothing, repellents, biological control (larvivorous fish, Bacillus thuringiensis), chemical control (larvicides: temephos, adulticides: pyrethrum, malathion)  | 
MUST READ ARTICLES
ALL YOU NEED TO KNOW ABOUT VIRUSES
Source:
https://www.who.int/news-room/fact-sheets/detail/zika-virus
https://my.clevelandclinic.org/health/diseases/16077-zika-virus
| 
 PRACTICE QUESTION 
 Which of the statements given above is/are correct? (a) 1 only (b) 1 and 2 only (c) 2 and 3 only (d) 1, 2, and 3 Answer: (b)  | 
								
								
								
								
								
								
								
								
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