NOBLE ROT

Researchers found Botrytis fungi, responsible for noble rot in wines, cannot be cloned because their complete set of chromosomes is unusually distributed across multiple nuclei, not contained within a single one. This discovery, published in Science, challenges established biological principles and is sparking new questions and excitement in fungal biology research.

Last Updated on 3rd July, 2025
3 minutes, 36 seconds

Description

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Picture Courtesy:  THE HINDU

Context:

Researchers found Botrytis fungi, responsible for noble rot in wines, cannot be cloned because their complete set of chromosomes is unusually distributed across multiple nuclei, not contained within a single one. 

What is Noble Rot?

Noble rot is a specific type of fungal infection crucial for producing some of the world's most exquisite and expensive sweet wines. The fungus responsible is Botrytis cinerea.

It infects ripe grapes, the infection causes the grape berries to lose water through evaporation. This concentrates the sugars, acids, and flavors within the grape.

Grapes affected by noble rot yield intensely flavored, high-quality sweet wines. Famous examples include:

  • Sauternes from Bordeaux, France
  • Trockenbeerenauslese from Germany and Austria
  • Tokaji Aszús from Hungary

Only a small percentage of grapes in a vineyard become infected, necessitating careful, manual picking. This labor-intensive process contributes significantly to the high cost of these wines.

Recent Discovery

The recent findings published in Science reveal a fundamental difference in the genetic organization of Botrytis cinerea and another related fungus, Sclerotinia sclerotiorum.

Traditional Understanding of Nuclei => In almost all animals, plants, and other fungi, each cell nucleus contains a complete set of all the organism's chromosomes (its entire DNA instructions). This is why scientists can clone organisms by transferring such a nucleus into an enucleated egg cell.

New Finding In Botrytis and Sclerotinia

Distributed Chromosomes => No single nucleus within these fungi holds all the chromosomes. The complete set of genetic information spreads out across multiple nuclei.

The unique chromosomal distribution directly explains why scientists cannot clone these specific fungi; there is no single nucleus containing all the necessary genetic information to initiate a new organism. 

 Source: 

THE HINDU

PRACTICE QUESTION

Q. Fungal toxins, or mycotoxins, pose significant health risks. Which of the following statements accurately describes a characteristic of fungal toxins?

A) Mycotoxins are produced by all fungal species as a primary metabolic function.

B) Fungal toxins are primarily proteins that are easily denatured by heat during cooking.

C) Aflatoxins, potent mycotoxins, are commonly produced by Aspergillus species on crops like peanuts and maize.

D) Fungal toxins are usually produced in symbiotic relationships to benefit the host organism.

Answer: C

Explanation: 

Aflatoxins are a well-known group of mycotoxins produced primarily by Aspergillus species, such as Aspergillus flavus and Aspergillus parasiticus. These fungi commonly contaminate important agricultural commodities like peanuts, maize (corn), cottonseed, and tree nuts, particularly in warm and humid conditions. Aflatoxins are potent, known for their carcinogenic properties and other adverse health effects in humans and animals.

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