HAVE DIRE WOLVES COME BACK FROM EXTINCTION?

Colossal Biosciences used gene editing to recreate dire wolf-like pups from grey wolves by modifying 14 genes. Though resembling extinct dire wolves, they lack natural survival skills and may not thrive. This raises ethical concerns about de-extinction and whether such recreated animals can adapt to modern ecosystems or survive long-term.

Last Updated on 10th April, 2025
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Colossal Biosciences brings back the dire wolf using advanced science.

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An American company ‘Colossal Biosciences’ announced they have brought back the dire wolf , an animal that went extinct over 13,000 years ago. However, they aren’t exactly the same dire wolves from history—they are more like genetically modified grey wolves made to look and act like dire wolves.

About Dire Wolves

They were big, powerful animals that lived during the Ice Age. They were taller than modern grey wolves (up to 3.5 feet tall), longer (over 6 feet), and weighed up to 68 kg.

They had white coats and hunted large prey like bison, horses, and possibly mammoths. 

How Did Colossal Bring Them Back?

Colossal didn’t clone a dire wolf. Instead, they used gene editing to make grey wolves resemble dire wolves. 

  • They Found Ancient DNA: Scientists got DNA samples from a 13,000-year-old tooth and a 72,000-year-old skull of dire wolves. These samples gave them enough genetic information to figure out what made dire wolves unique.
  • Compared Genomes: They compared the dire wolf genome to other canines (like grey wolves, coyotes, and jackals). It turns out grey wolves share 5% of their DNA with dire wolves, but there are still millions of tiny differences between them.
  • Edited Grey Wolf Genes: Using advanced technology, Colossal edited 14 genes in grey wolves to recreate traits of dire wolves, like their white coat, body size, and strength.
  • Made Baby Pups: After editing the genes, they created fertilized eggs and implanted them into surrogate dog mothers. Three pups were born: two males named Romulus and Remus, and a female named Khaleesi.

Will Dire Wolves Survive Again?

It is unlikely. Even though Colossal has created these pups, they are not fully equipped to survive in the wild. Without parents to teach them survival skills, and without a population to breed with, these animals might eventually die out again. This has happened before: in 2003, scientists cloned a Pyrenean mountain goat called the bucardo, but it died shortly after birth.

Colossal is also working on bringing back other extinct animals to restore ecosystems that lost key species thousands of years ago. However, critics worry about the ethics of de-extinction and whether these animals can truly adapt to today’s world.

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Source:

 INDIAN EXPRESS

PRACTICE QUESTION

Q. How does the concept of human dignity come into conflict with advancements in genetic modification? 150 words

https://t.me/+hJqMV1O0se03Njk9

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